Women's Health

Ginette-35

Cyproterone acetate with ethinyl estradiol can be used for the control of idiopathic hirsutism. Ginette-35 (cyproterone) in women who require anti-androgen therapy using oral contraceptives.

Ginette-35 0.035+2 mg

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Product description

Safety information

Side Effects

Drug Name

35 (cyproterone) Ginette

Drug Uses

Cyproterone acetate with ethinyl estradiol can be used for the control of idiopathic hirsutism.
Each blister strip of 28 tablets coated with 21 active hormonal 0035 mg ethinyl estradiol and 2 mg cyproterone acetate plus 7 inactive tablets non-hormonal, including bullets each.
Severe acne, especially in inflammation, androgen dependent, with the advent of nodes for the treatment of acne or seborrhoea. Ginette 35 women who require anti-androgen therapy using oral contraceptives.

How to use

The first shot of silver section (calendar pack) should be taken to start the day off to see a band show.
It is an open, normally closed but can be spontaneous. Use during the periodic medical examination is not recommended.
Missed dose: Take as soon as possible, which recently within the next 12 hours, but if it is almost time for your next dose.
And thromboembolic disease, family history of clotting system, especially at a young age, disorders should be excluded. Do not take a double dose.
Vomiting, diarrhea, or an additional non-hormonal contraception should be used to prevent pregnancy.
After the cycle: the new package after the completion of the last batch to be started again the next day began the day in the relevant part of the silver band.
The first cycle: the patient's first day of the cycle (first day of menstruation is the first day of the cycle) should take the first shot. Always return in time to prevent bleeding, take the next shot. Additional non-hormonal contraceptive precautions should be taken. One shot can be taken with food to reduce nausea.
The tablet should be taken at the same time almost every day for maximum effectiveness, not more than 24 hours.
Additional contraceptive precautions for 14 days before the first round or if the shot will be taken by mistake. Pregnancy must be excluded. Next, the pill must be taken every day, following a sequence of arrows, at the same time, until all the tablets are taken.
The patient should consult their doctor if the bleeding is persistent and long-term is recommended.
Tumor or adrenal enzyme defect to produce androgens to treat hirsutism Ginette-35 can not be excluded before prescribing. Ginette-35 is a first start, a proper medical examination (including gynecological) and the patient's medical history should be carefully evaluated.
As the dose contraceptives: androgen-dependent treatment of acne. This method should be followed when contraception is desired.

Drug Class and Mechanism

Is an anti-androgen cyproterone acetate.
Combined become hostile endometrium and endometrial implantation of a fertilized egg can make.
Cyproterone acetate causes increased viscosity of cervical mucus, making it hostile to sperm entry. Progestogenic activity and suppress the secretion of Gonadoatropins. Sebaceous gland activity is depressed in combination with cyproterone.
Ethinyl estradiol is a synthetic estrogen in combination with cyproterone well as suppressing the pituitary luteinizing follicle - stimulating hormone gland to release hormones to prevent ovulation, since the mid-cycle peak.

Missed Dose

Do not take a double dose. Ginette-35 you miss a dose, take as soon as possible, which recently within the next 12 hours, but it is almost time for your next dose. Additional non-hormonal contraceptive precautions should be taken. Always return in time to prevent bleeding, take the next shot.

Storage

Do not store in the bathroom. Shop 86 degrees F (30 degrees C) less than 35 Ginette. Heat, humidity and light from the store. Ginette-35 beyond the reach of children and pets away from himself.

Warnings/Precautions

Gain exposure in patients with endometriosis and uterine fibroids should be considered.
Known or suspected breast cancer. It is recommended that the oral contraceptive is out 4-6 weeks before major surgery. When the pressure is clearly the product should be closed.

6.
Liver disease or patients with tumors or wasting diseases. Women who use oral contraceptives should be strongly advised not to smoke.
COC in urine and plasma gonadotrophin concentrations returned to normal until after the recent evacuation of hydatidiform mole has decided not to do so.

5. Products frequent upper abdominal pain, jaundice, hepatitis or developed should be closed.
Hypersensitivity to any of the content.
Women smoke more than 15 cigarettes a day for at least 20% higher risk of serious cardiovascular side effects. Ginette-35 is highly recommended that if any of the following symptoms may occur off:

1. Migraine or severe headache at the beginning of a new patient. Smoking increases the risk of myocardial infarction.
Not for use in children and men.
7. Pregnancy.
2. There is a gradual or sudden loss of vision or hearing time.

4. Since the surgery or prolonged bed rest may increase the risk of thrombotic episodes.
Breast. Myocardial infarction, pulmonary embolism, deep vein thrombosis and stroke can join.
Unlike sickle cell disease, severe chronic depression and marked.

3. The first signs of thrombotic disorders, pulmonary embolism, cerebrovascular deficiency, thrombophlebitis, cerebral haemorrhage, retinal thrombosis, mesenteric artery thrombosis, or are, for example. Risk also increases with age and quite noticeable for women over age 35 years.

Opposite signs:
Known or suspected oral contraceptives should not be used during pregnancy because Northwest can cause serious damage.
Unlike oral contraceptives, estrogen dependent tumors, patients with functional ovarian cysts is indicated, Dubin-Johnson syndrome or Rotor, lipid metabolism, clear the liver function, cerebrovascular insufficiency, coronary heart disease, thrombophlebitis, disturbance otosclerosis worse, the history of pruritus last pregnancy, vaginal bleeding, herpes, recurrent cholestatic jaundice or undiagnosed porphyria.
Thrombotic disorders in patients with history should not be granted.
Patients with classic migraine should not be used in combination with oral contraceptives.
Relative of opposite sign (the patient requires medical supervision)
Diabetes mellitus, tetany, hypertension, epilepsy, Korean, multiple sclerosis, kidney disease, asthma, depression, varicose veins, heart disease, gallbladder disease in obese patients and patients that contact lenses, or other conditions affected by wear and tear fluid.

Possible Side Effects

There carbohydrate and lipid metabolism may be altered. Increased incidence of benign liver tumors, it seems.
May affect liver function. Observed in contact lens intolerance, and may worsen in patients with myopic vision.
After long-term use of oral contraceptives may amenorrhea.
Menstrual periods (spotting, breakthrough bleeding, amenorrhea), intermenstrual bleeding, a temporary change in libido, depressive mood changes and dizziness, abdominal cramps, or bloating may occur. Severe upper abdominal pain, liver enlargement, or the difference between the cases of stomach bleeding, liver tumors should be excluded. Thrombosis frequently blood group A, B or AB is with women. The following side effects may occur:
Most of the tenderness and secretions, including breast changes. Pre-treatment, including regular blood pressure check in Czech, is recommended. Occurrence of 1% of the users are fine.
The gall bladder obstruction, or hepatitis may occur.
The incidence of circulatory diseases combined oral contraceptive use among women is significantly higher than in controls, and mortality rates have risen slightly.
Malignant liver tumors have also been reported. If oligomenorrhoea or amenorrhoea have occurred in the past, caution should be exercised. Incidents increased in women who are obese or if they suffer from high blood pressure.
Cases of circulatory system diseases, diabetes and hyperlipoproteinaemia familial hypercholesterolemia occurs more in women.
Although the increased risk of cervical cancer has been reported that the other factors.
Hair pattern, skin reactions and changes in the onset of anemia.
High blood pressure can occur. Cerebrovascular accidents, coronary thrombosis, and venous thrombosis in women over the age of 35 years is likely, especially if they are 5 years or more are smokers or have used contraception. Nausea, vomiting, headache, chloasma, skin pigmentation, vaginal candidiasis, gastrointestinal upset, weight gain and peripheral edema.

More Information

There is evidence that the overall effect of vitamin C, extra large low-estrogen contraceptive high dose of birth control has changed. Bleeding, which, together with the return of high doses of vitamin C may
Some anticoagulants, antidepressants and diabetic medications can reduce the efficacy of cyclosporine and concurrent use may increase the plasma concentrations. The use of oral contraceptives during routine medical examinations should be. Some laboratory tests for the specific hormone tests, blood coagulation, thyroid function, glucose tolerance, liver function tests and serum triglyceride levels may be subject to change. Special precautions:
Before hormonal contraceptives are intended, ultimately, the patient, relevant health surveillance of his medical history should be evaluated carefully obey. Antihypertensives, beta-blockers and diuretics may be less than the effect of theophylline may increase the plasma concentrations of concomitantly. Bleeding or spotting possible signs of low contraceptive effect.
In no case, alternative methods of contraception should be taken off without contraception.
Oral contraceptive failure, griseofulvin, rifampicin may concomitantly with other antibiotics, and tetracyclines (ampicillin, amoxicillin, pivampicillin such), especially aminopenicillins.
Pregnancy in women has been reported in epilepsy (barbiturates, primidone, phenytoin, carbamazepine) will take. Long-term antibiotic treatment, but the first two weeks of antibiotics should take additional precautions.
Additional non-hormonal contraception during antibiotic treatment for seven days and should be recommended.

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